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Thanks Dr N for this review . I was always suspicious of the MTHFR fad in the early 00’s . I had many patients bring me their genetic testing results and wanted to take action about their MTHFR status. I sensed it was a bit of hype with our new found genetic analytic techniques. Now I understand more about it and have more to back me up as I try to reassure them. On another note- Did the article explain WHY Folic supplementation can mask B12 deficiency? I presume that fact has something to do with the linkage of THF and Methionine Cycles?

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