mRNA vaccines produce an unusually high fraction of IgG4 against spike. Some have falsely claimed this indicates tolerance developing against SARS-CoV-2. The truth of IgG4 is more complex.
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IgG4, COVID, and mRNA vaccines: Not so…
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mRNA vaccines produce an unusually high fraction of IgG4 against spike. Some have falsely claimed this indicates tolerance developing against SARS-CoV-2. The truth of IgG4 is more complex.